cis-Bis[N-(2-furoyl)-N′,N′-diphenylthioureato-κ2O,S]nickel(II)

cis-Bis[N-(2-furoyl)-N′,N′-diphenyl­thio­ureato-κ2 O,S]nickel(II)

In the title compound, [Ni(C(18)H(13)N(2)O(2)S)(2)], the Ni(II) atom is coordinated by the S and O atoms of two N-furoyl-N',N'-diphenyl-thio-ureate ligands in a slightly distorted square-planar coordination geometry. The two O and two S atoms are cis to each other.

2 - furoyl - LIGRLO - amide : A potent and selective Proteinase - Activated Receptor 2 ( PAR - 2 ) agonist

1-Furoyl-3-methyl-3-phenyl­thio­urea

The title compound, C(13)H(12)N(2)O(2)S, crystallizes with two independent mol-ecules in the asymmetric unit. The two mol-ecules differ in the conformation of the thio-carbonyl and carbonyl groups, and show the typical geometric parameters of substituted thio-urea derivatives. The crystal structure is mainly stabilized by inter-molecular N-H⋯O hydrogen bonding.

2 - furoyl - LIGRLO - amide : A potent and selective Proteinase - Activated Receptor 2 ( PAR

Synthesis and bioactivity of N-benzoyl-N'-[5-(2'-substituted phenyl)-2-furoyl] semicarbazide derivatives.

In order to find novel chitin synthesis inhibitors (CSIs) with good activity, benzoylphenylurea, a typical kind of CSIs, was chosen as the lead compound and 15 novel derivatives containing furan moieties were designed by converting the urea linkage of benzoylphenylureas into a semicarbazide and changing the aniline part into furoyl groups. The title compounds were synthesized by the reaction of...